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Anti-CCP (Cyclic Citrullinated Peptide) Antibody Test

In our body arginine normally metabolises and produces citrulline, but in conditions like rheumatoid arthritis, this conversion takes place rapidly, particularly in the joints. The citrulline alters the structure of the joint proteins and prompts an immune response, owing to which autoantibodies (cyclic citrullinated peptide antibodies) are produced again...

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Sample type

As advised

Gender

Male & Female

Age group

All age groups

Preparation

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Parameters

Test specific

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Anti-CCP (Cyclic Citrullinated Peptide) Antibody Test

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In our body arginine normally metabolises and produces citrulline, but in conditions like rheumatoid arthritis, this conversion takes place rapidly, particularly in the joints. The citrulline alters the structure of the joint proteins and prompts an immune response, owing to which autoantibodies (cyclic citrullinated peptide antibodies) are produced against the joint proteins in the body. A cyclic citrullinated peptide antibody test detects and measures the levels of these antibodies in the blood.


Why the test performed?

The test may be performed in association with or after a rheumatoid factor test to help diagnose rheumatoid arthritis and to evaluate its prognosis. The test may also be recommended to individuals with undifferentiated arthritis in order to assess their risk of developing rheumatoid arthritis.

When is the test ordered?

A physician may recommend a CCP antibody test in conjunction with a rheumatoid factor test if an individual experiences symptoms that may be owing to previously undiagnosed arthritis. The test may also be ordered following a negative rheumatoid factor test if signs and symptoms are indicative of rheumatoid arthritis. Such symptoms may include:
  • Fatigue
  • Fever
  • Pain in the neck, elbow, hips and knees
  • Swollen and painful joints of hands and wrists
  • The stiffness of joints in the morning.
  • How is the sample collected?

    A blood sample is collected from a vein in the arm.

    How to prepare for the test?

    No special preparation is required for the test.

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    Anti-CCP (Cyclic Citrullinated Peptide) Antibody Test availability by city

    Pricing and home collection availability may vary by city. Select your location to view the current booking options.

    Hyderabad

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    What our patients say

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    Frequently asked questions

    This test helps assess relevant health markers. Your doctor can interpret the result together with symptoms, history and other investigations.

    Preparation requirements can vary. Follow the instructions shown during booking or those provided by your doctor or Apollo Diagnostics.

    Home sample collection is available in supported locations. Availability is confirmed during booking based on your selected city and address.

    Reports are made available digitally after laboratory processing is complete. Report time can vary by test and location.

    A healthcare professional should interpret results that are abnormal, unexpected or associated with symptoms.

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